Preview the Nov. 8 matchup between the Indiana Hoosiers and Penn State Nittany Lions with predictions, odds, over/under, spread, betting lines and more.

The No. 2 Hoosiers look to stay unbeaten against a Penn State team trying to find itself following the firing of James Franklin

Indiana has one of, if not the best, offenses in the country. Penn State has struggled to stop any type of offense. Can that change this week?

FOX Sports' Laken Litman, RJ Young and Michael Cohen highlight the storylines at the center of this week’s "Big Noon Saturday" matchup.

PLAYER (S) ON THE SPOT: Penn State’s corners. If the Lions’ defensive backs allow Indiana’s wideouts to run past them the way Ohio State’s Jeremiah Smith and Carnell Tate did last Saturday, PSU will lose by four touchdowns.

The Big Ten's biggest stage comes to Beaver Stadium on Saturday, and Joel Klatt likes what the matchup says about both programs even if he's not tipping a winne

Penn State interim coach Terry Smith will lead the Nittany Lions (3-5, 0-5 Big Ten) as they try to snap a five-game losing streak against No. 2 Indiana (9-0, 6-0) on Saturday.

This Big Ten matchup was supposed to be one of the games of the year. Indiana and Penn State "could both enter this week undefeated". That didn't happen. James Franklin has been fired as Penn State's head coach.

Indiana, No. 2 in the season’s first playoff rankings, has outscored its last two opponents by a combined 111-16. Penn State, coming off a loss to No. 1 Ohio State, is one of four teams without a Big Ten win.

Penn State's offense has struggled during the losing streak and facing a tough defense shouldn't make it any easier. Do the numbers match the ranking?