Cancer remains one of the most strong challenges existing in modern medicine as of today, making it necessary to innovate strategies to combat its relentless progression. Out of the many strategies ...

The list of growth factors involved in tumor angiogenesis has grown substantially and includes vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), endostatin, ...

Researchers at Institute of Science Tokyo created a mouse model of the aggressive subtype of HCC and provided insights into its underlying molecular mechanism. Using these insights, they demonstrated ...

Nottingham, UK - Angiogenesis and inflammation are central players in the osteoarthritis (OA) disease process, and inhibiting both processes might alter OA progression, according to a review article ...

HIF-1α and BACH1 work together in the tumours, the new research shows. Hoping for more effective drugs "Many clinical trials have evaluated the efficacy of angiogenesis inhibitors, but the results ...

This phase I trial evaluated epigenetic modulation of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor by using a histone deacetylase abexinostat in combination with pazopanib to ...

This past February, for example, Sugen, a division of Peapack, NJ-based Pharmacia, announced it was aborting its Phase III colorectal cancer clinical trial of SU5416, as no clinical benefit was found.

Systematic Review of Pretreatment Prostate-Specific Antigen Velocity and Doubling Time As Predictors for Prostate Cancer We performed a retrospective radiologic review of patients with NSCLC enrolled ...

Copper complexes acting angiogenesis inhibitors have been disclosed in a patent from Istinye Universitesi and Karadeniz Teknik Universitesi Teknoloji Transferi Uygulama ve Arastirma Merkezi as ...

A new study has found that antioxidants like vitamins C and E activate a mechanism that stimulates the growth of new blood vessels in cancer tumors, helping them to grow and spread. The researchers ...