The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

Increased expression of the Ang‐II (Angiotensin II) precursor AGT in aged astrocytes lead to increased Ang‐II signaling from aged astrocytes to endothelium, thus increasingblood–brain barrier (BBB) ...

A key aspect of Parkinson’s disease (PD) pathophysiology is decreased systemic regulatory T cell (Treg) function with associated neuroinflammation in the nigrostriatal pathway of the brain, including ...

Major depressive disorder (MDD) is a mental health condition that negatively affects the mood of a person and causes a loss of interest in activities that were previously associated with happiness. In ...

Cedars-Sinai investigators have discovered a healing mechanism that could one day be harnessed to help treat patients with spinal cord injuries, stroke, and neurological conditions such as multiple ...

Fascinating new findings into how clusters of 'brain stars' retain memories has changed what we know about how they're held in our minds. Baylor College of Medicine researchers have been investigating ...

A study published in Nature by researchers at Baylor College of Medicine changes the way we understand memory. Until now, memories have been explained by the activity of brain cells called neurons ...

A collaborative French–Swiss study reveals a previously unknown role for astrocytes in the brain's information processing. Published in the journal Cell, the research shows that these glial cells are ...

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare. Patients ...

Inflammatory bowel diseases (IBDs), such as Crohn's disease and ulcerative colitis, are chronic and autoimmune conditions characterized by the inflammation of the intestinal tract. This inflammation ...