Bacterial gene regulation is a finely tuned process essential for cellular adaptation and survival. Central to this regulation are nucleoid-associated proteins (NAPs), which not only compact the ...

Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation. Bacterial infections cause millions of deaths each year, with the global threat ...

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...

Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by chemist Brian Liau and his collaborators at Harvard offers an ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 40 (October 4, 2022), pp. 1-9 (9 pages) Horizontal gene transfer drives bacterial evolution. To confer ...

An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs. An international collaboration has ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...

Washington, D.C. – A new study, “Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein” published in Biochemistry, provides key insights into how bacterial cAMP receptor ...

Deep within the world's oceans lurk marine bacteria armed with plastic-munching enzymes, their evolution seemingly sculpted ...

Epigenome editing has followed a similar path, in that more recent technological breakthroughs have enabled scientists to apply the discoveries made in previous decades. Epigenome editing performs a ...

Everyday substances, including caffeine, can trigger changes in bacteria like E. coli that make antibiotics less effective. Caffeine activates a regulatory path involving a bacterial protein called ...