Bacterial gene regulation is a finely tuned process essential for cellular adaptation and survival. Central to this regulation are nucleoid-associated proteins (NAPs), which not only compact the ...

Researchers are one step closer to understanding how some plants survive without nitrogen. Their work could eventually reduce ...

Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...

Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by chemist Brian Liau and his collaborators at Harvard offers an ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 40 (October 4, 2022), pp. 1-9 (9 pages) Horizontal gene transfer drives bacterial evolution. To confer ...

Analysing the gene activity of every single bacterial cell in a colony? A new technique of single-cell transcriptomics developed in W rzburg can do this much more efficiently than other methods: It ...

Given the growing antibiotic resistance crisis, novel ways to target bacterial infections are becoming increasingly important. One potential strategy is to manipulate bacterial genes at the ...

If corn was ever jealous of soybean's relationship with nitrogen-fixing bacteria, advancements in gene editing could one day even the playing field. A recent study shows that gene-edited bacteria can ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...

Epigenome editing has followed a similar path, in that more recent technological breakthroughs have enabled scientists to apply the discoveries made in previous decades. Epigenome editing performs a ...