How our bodies break down and remove old and damaged bone tissue is linked to our inner circadian clock, according to a new study from the University of Surrey and the University of Sheffield. The ...
Periodontitis is the leading cause of tooth loss, with alveolar bone resorption serving as its fundamental pathological feature. Identifying key regulatory genes and molecular mechanisms is essential ...
Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...
Researchers at Osaka University show that intercellular communication via extracellular vesicles from bone-making osteoblasts is a key factor for the switch from bone formation to resorption through a ...
Despite the tremendous efforts of researchers studying bone remodeling for more than 50 years, the intrinsic spatial, biomolecular, and mechanotransduction complexities in bone remodeling continue to ...
These resorption and formation phases are linked and balanced with intermittent coupling phases. "Functional coupling between these two cell types is critical for the maintenance of proper bone ...
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