A newly identified enzyme appears to control tau production, brain inflammation, and aging. Researchers at the University of ...

In neurodegenerative diseases, microglia can help or harm the brain. In the October 3 Journal of Clinical Investigation, scientists led by Ilia Baskakov at the University of Maryland School of ...

University of New Mexico researchers found that the immune enzyme OTULIN drives tau production, brain inflammation and aging.

Whether by way of a soccer ball or another player’s head, sustaining too many whacks to the noggin leaves a visible mark on the brain. This was the common conclusion of two very different studies that ...

A new study links repeated binge drinking to persistent brain inflammation that reshapes mood, fear learning, and relapse ...

SAN FRANCISCO—In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein—the most important genetic risk ...

In chronic neurodegeneration associated with prion disease, reactive microglia adopt a highly mobile, neuron-by-neuron surveillance strategy, replacing homeostatic process-based monitoring with ...

Research led by the SickKids Research Institute in Toronto and the University of Pennsylvania, has found that immune-related ...

Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures ...