Tumor growth is associated with profound metabolic and neurochemical alterations, which can lead to the onset of anorexia−cachexia syndrome. Anorexia is defined as the loss of the desire to eat, while ...

Many people with cancer experience dramatic loss of muscle and fat tissue. In many cases, even the heart muscle is affected, which further weakens the body. This wasting syndrome, known as cachexia, ...

Inflammatory marker levels and prediction of patient-reported symptoms in patients with advanced pancreatic cancer receiving gemcitabine-based chemotherapy. This is an ASCO Meeting Abstract from the ...

A recent Nature Metabolism study reports that circulating lactate levels are positively associated with weight loss in cancer cachexia patients. Mouse model experiments also revealed that ...

Anti-cachectic effects of a novel peptide nucleic acid: Preliminary results of a phase 1/11 clinical trial Authors: J. T. D'Olimpio, S. Z. Hirschman, Z. Shtemer, and M. Didiego Authors Info & ...