Chronic illnesses such as cancer and autoimmune disorders significantly strain both patients and healthcare systems. Traditional long-term drug therapies, which often have non-specific effects, can ...

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, self-perpetuating state of inflammation. Emerging work now suggests that aging immune ...

The idea of self-amplifying gene editing is to get cells to pass on packages of CRISPR machinery to their neighbours, boosting the effect ...

Sickle cell disease (SCD) is a genetic condition that affects more than 8 million people worldwide by altering the shape of oxygen-carrying red blood cells. Normally, red blood cells are shaped like ...

Editas Medicine reports successful gene editing levels in stem cells, supporting potential treatment for sickle cell disease and beta thalassemia. Editas Medicine announced promising new data on May ...

Having sickle cell disease used to mean Alyssa Weddle missed out on normal teenage things — going out with friends, school work, extracurricular activities. Now, after gene editing therapy, it’s been ...

Enveloped viruses get their outer coat by budding from cells they've invaded. CRISPR-Cas9 researchers coopted this behavior to produce envelope-derived vehicles that encapsulate Cas9 proteins (dark ...