Computational Chemistry is the study of complex chemical problems using a combination of computer simulations, chemistry theory and information science. Also called cheminformatics, this field enables ...

The process of discovering and designing new chemicals has always been arduous—Sijia Dong wants to change that. As an assistant professor in the department of chemistry and chemical biology, with ...

For Tim Cernak of the University of Michigan, small certainly is beautiful. He and his colleagues have redesigned some of the most popular reactions in medicinal chemistry so that they work in ...

Targeted drugs aim to pinpoint the exact location in the body where diseased tissue is located and where the medicine is required. The manifold benefits of administering a targeted drug include ...

Covalent chemical probes – chemical probes that form a covalent bond with their target biomacromolecule(s) represent powerful tools that can be used for biology discovery, target validation (or ...

Triple click chemistry has revolutionized chemical synthesis with its simplicity and efficiency, allowing for the quick and selective assembly of complex molecules. Now, in a recent study, researchers ...

Medicinal chemistry, also known as pharmaceutical chemistry, is a branch of chemistry focused on the development of new drugs and the improvement of existing ones. It is an interdisciplinary field ...

A new microscopy method enables researchers to visualize the activity of the enzymes caspase-3 and alkaline phosphatase in various biological samples (Nat. Methods 2024, DOI: ...

The new method builds on a framework called the Localized Active Space (LAS) approach, originally developed by Research Assistant Professor Matthew Hermes. By extending it to periodic solids, the team ...

Moffitt Cancer Center researchers have developed a novel reagent that enhances the precision of drug synthesis. This innovative method, published in Nature Communications, introduces a new sulfur ...

The 2022 Nobel prize in chemistry has been awarded to a trio for developing click chemistry, an environmentally friendly method for rapidly joining molecules to develop cancer treatments, create ...

Carolyn Bertozzi of Stanford University, Morten Meldal of the University of Copenhagen, and K. Barry Sharpless of Scripps Research won the Nobel Prize in chemistry on Wednesday “for the development of ...