Soft tissue tumours and lesions characterized by USP6 gene rearrangements represent a heterogeneous group of neoplasms that include nodular fasciitis, aneurysmal bone cysts, cellular fibroma of tendon ...
This figure depicts how bridge recombinases have a dual targeting capability that enable these systems to insert new genetic material, delete unwanted regions, or flip existing DNA segments all in a ...
Researchers reprogrammed bacterial bridge recombinases to edit large genomic regions in mammalian cells, revealing a ...
Publication shows that OGM can resolve translocation partners involving MYC in multiple myeloma (MM) more effectively than current methods The release of compelling data in MM underscores the ...
Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...
Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...
OGM was selected as a genome-wide, unbiased method to detect large genomic rearrangements and structural variants (SVs) with sensitivity to variant allele fractions (VAFs) as low as 5% to analyze ...
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