KAUST scientists use cryogenic electron microscopy to investigate the 3D structure and function of key protein complexes involved in DNA replication and repair. Credit: KAUST; Heno Hwang KAUST ...

According to the researcher, significant differences were found, for example, in the onset and duration of DNA replication and in the production of proteins that regulate the cell cycle. These ...

Sarah J. Aitken is at the Center of Molecular and Cellular Oncology, Yale Cancer Center, New Haven, Connecticut 06511, USA, and in the Department of Pathology, Yale School of Medicine, New Haven. Read ...

Standard genetic sequencing approaches can tell you a lot about the genetic makeup and activity in a sample, like a piece of tissue or drop of blood. But they don't tell you where specific genetic ...

Researchers at California NanoSystems Institute at UCLA, Stockholm University and Uppsala University are working on a smartphone-based microscope in hopes of developing a cost-effective and accessible ...

Scientists often describe life as a series of chemical reactions. Pallav Kosuri, Ph.D., describes life as movement. Chemical reactions are how you drive the movement of atoms, proteins, cells and ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

A new microscope sensitive enough to track the real-time motion of a single protein, right down to the scale of its individual atoms, has revealed how genes are copied from DNA – a process essential ...

During replication, DNA polymerases are positioned on each strand of DNA. Using a microscope slide as an anchor, we tethered DNA to a bead and stretched it with a flow of solution. We tracked how the ...