To aid in assessing the impact of chemicals and drugs on cilia function in the small airway epithelium, the lung cilia beat frequency analysis in vitro assay is the ideal option. Using the ...

"This is a clear target that could be used to upregulate ciliary beating in the airways," said Jékely. Conversely, in asthma, where epithelial airway surfaces become inflamed and irritated, drugs ...

In many cells of the human body, hair-like protrusions known as cilia act as antennae, allowing cells to receive signals from their environment and other cells. As cells grow and divide, each cilium ...

The motile cilia that line the epithelial tissue of the airways are considered the first line of defense against pathogens that cause several respiratory diseases. The airway epithelium consists of ...

Loss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Ciliopathies are multisystem disorders ...

Many cells in our body have a single primary cilium, a micrometer-long, hair-like organelle protruding from the cell surface that transmits cellular signals. Cilia are important for regulating ...

This schematic shows that the PEG-BB molecules — the bottlebrush-shaped objects — move through and past the mucus and periciliary layers to be internalized by cells across the whole epithelial layer.

A joint team of researchers from Constructor University and Constructor Technology have harnessed the power of machine learning to uncover new findings about human thyroid health. In a new study ...