Nature

Enhanced transgene expression in primitive hematopoietic progenitor cells and embryonic stem cells efficiently transduced by optimized retroviral hybrid vectors

To dissect the molecular cause of human diseases and to develop novel therapeutic strategies retroviral reconstitution of genes in pluripotent cells is of great importance. Although the Moloney murine ...
Nature

Ectopic FOXP3 Expression Preserves Primitive Features Of Human Hematopoietic Stem Cells While Impairing Functional T Cell Differentiation

FOXP3 is a forkhead transcription factor controlling the gene expression patterns needed for the function of T regulatory cells (Treg), the main cell subset maintaining peripheral immune tolerance 1.
ascopubs.org

TrkC Expression Predicts Good Clinical Outcome in Primitive Neuroectodermal Brain Tumors

Serum Human Glandular Kallikrein-2 Protease Levels Predict the Presence of Prostate Cancer Among Men With Elevated Prostate-Specific Antigen PURPOSE: To identify biologic prognostic factors in ...