A team of UK-based researchers is going where no scientist has dared to go—writing artificial human DNA from scratch. They’re hoping the project will answer fundamental questions about the human ...

The ability to sequence and edit human DNA has revolutionized biomedicine. Now a new consortium wants to take the next step and build human genomes from scratch. The Human Genome Project was one of ...

Scientists can choose between multiple human genome references, and a pangenome reference is coming. Deciding what to use when is not quite straightforward. You have full access to this article via ...

Leading synthetic biologists have shared hard-won lessons from their decade-long quest to build the world's first synthetic eukaryotic genome in a Nature Biotechnology paper out today. Their insights ...

We mapped the human genome decades ago, but most of it is still a black box. Now, UNSW scientists have developed a tool to peer inside and what they find could reshape how we think about disease. Your ...

Sudarshan Pinglay is a synthetic biologist who leads a research laboratory affiliated with the University of Washington and the Seattle Hub for Synthetic Biology in Seattle, Washington. Ten years ago, ...

HERRO was designed to be haplotype-aware, meaning it improves the accuracy of ONT Simplex reads while preserving the genetic differences that distinguish one chromosome copy from the other. This helps ...

Early in development, a group of migrating cells called cranial neural crest cells go on to form many different parts of the face, including the nose, jaw, ears, and throat. To build these structures ...