A team of Chinese researchers has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems. The study, published online in Cell on August ...

New tools aim to turn DNA into something engineers can design ...

Chinese Hamster Ovary (CHO) cells have been the industrial workhorse for production of biopharmaceuticals since the 1980s, with the first CHO-derived product approved by the FDA in 1987. Nearly five ...

Changing an organism’s genome is a profound act, and the tools you use to make the changes don’t alleviate the need for responsible regulation. Unlike “traditional” genetically modified organisms (GMO ...

Earth's biodiversity is in crisis. An imminent "sixth mass extinction" threatens beloved and important wildlife. It also threatens to reduce the amount of genetic diversity—or variation—within species ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

Across biomanufacturing, disease modeling, synthetic biology, and cell therapy development, researchers increasingly need to insert large DNA constructs into mammalian genomes. Yet despite significant ...

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field. While existing editing ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions -- but there is always room for improvement. A new paper showcases the power of scalable protein ...

A team of Chinese researchers has developed two new genome editing technologies, known collectively as Programmable Chromosome Engineering (PCE) systems. Subscribe to our newsletter for the latest sci ...