Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...
DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...
CHICAGO --- In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed ...
Four Northwestern scientists published a study in December as part of the 4D Nucleome Project, which maps the genome in 3D ...
University of Wisconsin researchers Sushmita Roy and Erika Da-Inn Lee have developed a new computational tool that maps changes in the genome, ultimately helping researchers see DNA’s 3D organization ...
In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...
University of Toronto researchers have developed a new computational method to study how chromosomes within human cells are organized. The method could help advance precision medicine by shedding ...
Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...
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Data-driven modeling uncovers dynamic genome folding in three dimensions
Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren't ...
The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...
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