New research reveals that sleep deprivation sends aberrant signals through the vagus nerve, triggering a serotonin surge that can kill gut stem cells.

Researchers at Baylor College of Medicine, the University of Michigan and collaborating institutions have discovered that inflammation in the gut leaves long-term marks on intestinal stem cells (ISCs) ...

Supplementing the guts of older mice with poop from younger ones has revealed the key role microbes play in intestinal stem cell function. After receiving a fecal microbiota transplant from younger ...

Chronic sleep disruption doesn't just leave people tired and irritable. It may quietly undermine the gut's ability to repair ...

A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline. The ...

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at the base of crypts.

Drosophila melanogaster has long served as a powerful model for dissecting the principles of tissue homeostasis and regeneration. Within the adult midgut, intestinal stem cells (ISCs) perform the ...

Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Image Caption: The signaling pathways involved in the intestinal stem cell niche and cell fate determination. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...