A research group has identified the so-called PNOC/NPY nerve cells in the brains of mice. When activated, these cells increase food intake and lead to obesity. Interestingly, these nerve cells are ...
New research in iScience shows that the hormone leptin, the potassium channel Kcnb1, and integrins form a tripartite brain ...
Leptin, a hormone produced chiefly by adipose tissue, plays a central role in coordinating energy balance, immune responses and vascular homeostasis. Beyond its well-characterised functions in ...
A team of scientists has uncovered a critical mechanism that could pave the way for safer and more effective obesity treatments. The findings, published in Nature Communications, shed light on how ...
Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have ...
NEW YORK – New research from Columbia University Medical Center has illuminated a previously unknown leptin-serotonin pathway in the brain that simultaneously promotes appetite and bone mass accrual.
Three decades ago, in a lab at The Rockefeller University, New York City, Jeffrey Friedman, MD, PhD, observed a paradox that would forever change our understanding of obesity. His subjects, a rare ...
Four years after its discovery, the weight-controlling protein hormone leptin is still making news. At the American Diabetes Association meeting in Chicago June 14, researchers from Amgen Inc. of ...
Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation
In a recent study published in Molecular Metabolism, researchers investigated whether under chronic [in obese mice with leptin-associated ob gene mutation (ob/ob)] or acute [six hours of fasting in ...
ANN ARBOR, Mich. -- Twin epidemics of obesity and type 2 diabetes are bearing down on the world's population, threatening the lives of hundreds of millions of people. But scientists are still trying ...
Scientists at Pennington Biomedical Research Center have gained greater clarity in the brain regions and neurons that control metabolism, body temperature and energy use. Featured in the February ...
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