In a breakthrough for cardiovascular medicine, researchers have harnessed artificial intelligence to discover unexpected lipid-lowering effects in existing FDA-approved drugs. The study, published in ...

Lipid nanoparticles consist of spherical vesicles made of ionizable lipids with a positive charge at a low pH level, while being neutral at a physiological pH. Such a characteristic enables RNA ...

Aircraft wing-shaped structures inside tiny channels produce consistent drug delivery particles at any scale, from small laboratory tests to factory production, while substantially cutting costs.

Lipid nanoparticle formulation has increased over the past two decades. LNPs have proven to be effective nano-based delivery vehicles for cytotoxic chemotherapeutic drugs, nucleic acid therapies and ...

“We’ve never had such an in-depth map of the CD1 lipidome available,” said Patricia Barral, an immunologist at King’s College London who was not involved with the work. “It will enable us to start ...

Lipids are fatty compounds that perform a range of essential functions in the body. Phospholipids, steroids, and triglycerides are examples of lipids. Although lipids play an essential role in the ...

New research from scientists at the University of Pennsylvania shows that by tweaking the structure of the ionizable lipid component of lipid nanoparticles (LNPs), they can reduce side effects such as ...

Inflammation sits at the heart of everything from sprained ankles to heart disease, yet medicine has long struggled to switch it off without blunting the immune system entirely. Now scientists have ...