Inspired by the natural bonding between a class of potent local anesthetics called site-1 sodium channel blockers (S1SCBs) and peptide sequences on the sodium channel in the nerve cell membrane, ...

Local anesthesia is a better option than general for reducing complications and increasing comfort in patients undergoing transcatheter aortic valve replacement (TAVR), according to a registry study ...

Warming local anesthetics may reduce pain experienced during injections, according to a study published in the Annals of Emergency Medicine. The study, authored by Anna Taddio, MD, of the University ...

Patients given ester-based local anesthetics may be at greater risk of having serious complications when they are administered numbing agents, according to a study published on March 31 in the ...

Local anesthesia is safe and effective for oculofacial surgery, according to an OSN Supersite report. Anesthesia for eyelid and periocular surgery necessitates safety to the eye, optic nerve and other ...

Local anesthetics have transformed clinical practice by enabling a broad range of minor and major procedures with minimal discomfort. Although adverse reactions are frequently reported, genuine ...

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties. They provide pain relief without toxic effects on local nerves and ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

NEW ORLEANS, LA—Going with a minimalist approach that involves local instead of general anesthesia appears to have several advantages for patients undergoing TAVR, according to a new meta-analysis. In ...

Inflammatory bowel disease (IBD) is a chronic disease of the intestines and no definitive medical treatment has been defined yet. A research team from Turkey applied local anesthetics onto the ...

Local anesthetics bupivacaine and lidocaine have been in unsteady supply since at least 2015, and recently, drugmakers postponed their expected resupply dates again. For six of Pfizer’s bupivacaine ...