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Rebuilding genomics workflows around long-read sequencing

Short-read sequencing built the modern genomics era. Illumina platforms, generating millions of short DNA fragments in ...
The Scientist

Optimizing Oxford Nanopore Long-Read Whole Genome Sequencing of Salivary DNA Using Oragene™ Collection Devices

Oxford Nanopore long-read sequencing helps researchers derive insights from difficult-to-read genomic sections and detect large structural variants. However, the technique uses high molecular weight ...
The Scientist

Meeting Modern Lab Demands with Flexible Any-Read Length Sequencing

In 1977, biology was forever changed when Frederick Sanger developed chain-termination sequencing and decoded the first complete genome of the bacteriophage φX174. 1 What began as a breakthrough ...
Technology Networks

Next-Generation Sequencing: How It Works, Platforms, and Applications

A complete guide to next-generation sequencing: the chemistry behind major platforms, how libraries are built, data analyzed, ...
BioTechniques

How long-read sequencing is scaling beyond the specialist lab

Here, Aaron Wenger, Principal Scientist – Bioinformatics at PacBio (CA, USA), explores how advances in accuracy, throughput and cost are making long-read sequencing more accessible at scale. Advances ...
GEN

The Throughput Paradox: Why Next-Generation Sequencing Bottlenecks Persist Beyond the Sequencer

The landscape of next-generation sequencing (NGS) continues to be defined by astonishing technological progress. We continue to witness sequencer throughput expansion with systems like the Illumina ...