Less than 30% of people with certain genetic variants go blind, despite the faulty genes previously being thought to cause ...

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

. For about a century, the argument for focusing on rare Mendelian disorders was as follows: Mendelian phenotypes will reveal genes involved in common multifactorial traits, metabolic pathways ...

Increased BMI and IBD have causal effects on the risk of hidradenitis suppurativa, as shown by Mendelian randomization ...

Mendelian randomization is a study design that uses genetic variants as instrumental variables to test the causal effect of a (non-genetic) risk factor on a disease or health-related outcome. Since ...