New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying ...

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide. But much remains unknown about the roots of anxiety in the brain. Now, ...

Researchers have uncovered surprising evidence that anxiety may be controlled not by neurons but by two dueling groups of immune cells inside the brain. These microglia act like biological pedals—one ...

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide. But much remains unknown about the roots of anxiety in the brain. Now, ...

(Left) Correction of pathogenic Csf1r mutation by Mr BMT effectively rescues pathological changes in the brain, motor impairment and cognitive decline in ALSP mice. (Right) tBMT-mediated microglia ...

Depression affects millions worldwide, yet its root cause has long remained elusive. Behind its lived experience lies a biological mystery: Why does the brain, an organ built to adapt and survive, ...

In the search for answers about Alzheimer’s disease, researchers are taking a close look at the immune system of the brain. A new study uncovers how a key immune cell, called a microglia, might be the ...

Brain macrophages serve diversified niches in the brain to maintain the organ’s homeostasis, and can play pathogenic roles in age-related brain disease. Hoping to one day replace dysfunctional ...