New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying ...
Neurodegenerative diseases, traditionally viewed as driven by neuronal decline, are increasingly recognized to involve ...
Microglial activation is a determining factor that allows amyloid-beta accumulation to drive reactive astrogliosis, amplifying inflammatory responses in the brain. This was the conclusion of a study ...
Results confirm positive signal previously reported in the first two Expanded Access patients who both subsequently demonstrated clinical improvements Phase 2a trial in na-SPMS on track to begin in Q3 ...
“These are the first data to link ASC speck assembly, NLRP1 inflammasome activation, and alpha-synuclein aggregation in neurons of Parkinson’s disease patients,” said Stephen C. Glover, ZyVersa’s ...
Move over, amyloid, reactive astrocytes and activated microglia may be the main drivers of the Alzheimer’s disease pathological cascade. In the November 6 Nature Neuroscience, scientists led by Pedro ...
New research published in Brain, Behavior, and Immunity provides evidence that alcohol use disorder triggers a distinct type of immune response in the brain. The findings suggest that excessive ...
Good managers set the tone for the whole team, encouraging positive behavior from everyone around them. In the November 5 Nature, scientists introduce a subtype of microglia that appears to do just ...
In recent years, there's been a growing awareness of neuroinflammation, an immune response in the brain. Research suggests that chronic inflammatory activation could be a central driver behind many ...