New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying ...

Researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study also integrates drug databases with real ...

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed ...

In chronic neurodegeneration associated with prion disease, reactive microglia adopt a highly mobile, neuron-by-neuron surveillance strategy, replacing homeostatic process-based monitoring with ...

A 30% calorie reduction over decades slows brain aging in monkeys by preserving microglia and oligodendrocytes, new research ...

When young donor myeloid cells are transplanted into aging mouse brains, they quickly adopt aging phenotypes. In contrast, old myeloid cells transplanted in young brains take on a more youthful aspect ...

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide. But much remains unknown about the roots of anxiety in the brain. Now, ...

Researchers at Karolinska Institutet have discovered that the nervous system's own immune cells help protect the spinal cord ...