The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill, explains how nerve and muscle signaling in the neuromuscular junction go awry in myasthenia gravis.

A recent review article titled "The Role of Rapsyn in Neuromuscular Junction and Congenital Myasthenic Syndrome" has been published by researchers from Nanchang University in China. Led by first ...

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...

The new research could help identify ways to preserve neuromuscular junctions. Muscle-specific kinase (MuSK) is essential to the development of functional neuromuscular junctions, but scientists have ...

Findings published in The American Journal of Pathology identify GLUD1 enzyme as a potential therapeutic target for muscle restoration through metabolic reprogramming, addressing clinically unmet need ...

This is a preview. Log in through your library . Abstract Hybridoma techniques have been used to generate monoclonal antibodies to an antigen concentrated in the basal lamina at the Xenopus laevis ...

A small molecule previously shown to enhance strength in injured or old laboratory mice does so by restoring lost connections between nerves and muscle fibers, Stanford Medicine researchers have found ...