During the assembly of the nervous system, neurons extend axons over long distances to reach appropriate targets and form functional circuits. This process is guided by growth cones—dynamic structures ...

Brain function requires exquisitely adapted plasticity at multiple scales, from synapses to whole-brain networks. Evidence for large-scale plasticity in functional brain networks comes from ...

Effective axon regeneration is critical for restoring nerve function in patients with axon injury-related neurological diseases, yet adult mammals show limited regenerative capacity in central axonal ...

A new study in zebrafish reveals that the gene nexmifb—a paralog of the human neurodevelopmental gene NEXMIF—plays a critical role in spinal motor neuron development by modulating the axon guidance ...