The transcription factor p53 is the most frequently inactivated tumour suppressor in cancer. Approaches to restore its wild-type function are challenging and have not led to approved drugs. An ...
In a groundbreaking review published in Current Molecular Pharmacology, a team led by Dr. Jhi Biau Foo from Taylor’s University unveils the pivotal role of mutant p53 (mutp53) in driving cancer ...
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