Phosphatidylinositol 3,4,5-trisphosphate (PIP3) and PIP3 phosphatase (PTEN) are enriched mutually exclusively on the anterior and posterior membranes of eukaryotic motile cells. However, the mechanism ...
The alternative text for this image may have been generated using AI. In summary, we have revealed a function for IFITM3 as a PIP3 scaffold in the amplification of PI3K signalling. In Ifitm3 −/− B ...