The activation and deactivation of apoptosis is a promising field of research in basic biomedical research. The team led by Prof. Franz Hagn from the Chair of Structural Membrane Biochemistry at the ...

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It ...

A collaborative research group has developed a novel therapeutic candidate that may improve the prognosis of severe cutaneous ...

Selective ASO-based JAK2 inhibitor for the treatment of hematological malignancies with JAK2 V617F mutation burden. Use of causal modeling to uncover cell-cell communication dynamics in the tumor ...

In the fight against disease, programmed cell death - also known as apoptosis - is a key protective function of the body. It ...

Combining proteasome inhibitors with autophagy inhibitors disrupts acute myeloid leukemia (AML) cells' proteostasis, ...

A recent trial evaluates the impact of dostarlimab on ovarian cancer treatment, revealing modest benefits and no significant safety concerns with niraparib.

The regulation of cell death is fundamental to both organismal development and the maintenance of tissue homeostasis. Among the various modulators of cell death, Bax inhibitor proteins have emerged as ...

Discovery of inhibitors that suppress disease-specific keratinocyte death and demonstration of their efficacy in preclinical ...

The US Food and Drug Administration (FDA) has granted approval to Regeneron Pharmaceuticals’ fully human monoclonal antibody Libtayo.

Inhibrx Biosciences is vying for approval of its targeted therapy, ozekibart, in chondrosarcoma. This follows the positive ...