BIOENGINEER

RNA Splicing Factor SRSF1 Emerges as a Powerful New Regulator of Aging

A transcriptomic reprogramming screen has identified the RNA splicing factor SRSF1 as a conserved regulator of aging that ...
BIOENGINEER

RNA-Binding Protein HuR Emerges as a Master Switch in Tau Splicing and Alzheimer’s Genes

A new study identifies the RNA-binding protein HuR as a repressor of tau exon 10 splicing and a regulator of ...

Envisagenics Awarded $2M+ NCI SBIR Grant to Expand AI-Driven RNA Splicing Analysis Capabilities Across Oncology Portfolio

Funding will advance translational readiness across Envisagenics’ cancer-specific programs for internal development and ...
Fred Hutch

RNA “typos” can highlight leukemia cells for immune attack

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...
Phys.org

AI-driven framework enables precise prediction of RNA splicing and isoform usage

RNA is the means of translating the genetic code embedded in DNA into proteins, which serve as enzymes, transporters, signaling molecules, receptors, structural components, regulators, and ...

Sarepta Therapeutics Presents New Preclinical Data Demonstrating Robust Knockdown of Pathogenic DMPK RNA in the Nucleus with SRP-1003 in DM1 at 2026 Oligonucleotide ...

Sarepta Therapeutics, Inc. (NASDAQ:SRPT), the leader in precision genetic medicine for rare diseases, today presented new preclinical data at the 22nd Annual Meeting of the Oligonucleotide ...
Phys.org

Biologists discover a new type of control over RNA splicing

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...
Medical Xpress

RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading. However, many individuals develop resistance to few ...

The Genome’s Hidden Layer

A study finds that mammalian cells can join RNA from separate genes into functional hybrid proteins, revealing a hidden layer of genome complexity in immune cells.

Akari Therapeutics Expands Intellectual Property Portfolio with PCT Filing for ADC Payload Related to RNA Splicing in Cancers

Patent filing covers PH1 payload’s unique ability to disrupt multiple cancer-driving pathways in addition to its overall ...
Medical Xpress

Alternative RNA splicing tied to schizophrenia-like behaviors in animal models

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia. The research was conducted by scientists led by LI Ming ...
MarketScreener

Sarepta Therapeutics, Inc. Presents New Preclinical Data Demonstrating Robust Knockdown Of Pathogenic DMPK RNA In The Nucleus With SRP-1003 In DM1 At 2026 Oligonucleotide ...

Sarepta Therapeutics, Inc. presented new preclinical data at the 22nd Annual Meeting of the Oligonucleotide Therapeutics Society (OTS) demonstrating that SRP-1003, the company's investigational small ...