P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical Research Institute (IRCM) and the Maisonneuve-Rosemont Hospital Research Center ...

The team of researchers led by Prof. Kristian Franze found that increasing tissue stiffness induces the expression of chemical signals that are typically absent in those regions. Semaphorin 3A is one ...

In a major brain science breakthrough, New Orleans-based researchers and collaborators have discovered a nerve signaling mechanism that takes place outside the cell, flipping on a 'pain switch.' This ...

Plants mobilize their immune defenses far earlier than scientists have believed for decades—and through a previously overlooked early signaling mechanism—according to a new study published in Nature ...

Retinal degeneration leads to irreversible vision loss, significantly impacting quality of life. Approximately 19.83 million Americans over 40 have age-related macular degeneration (AMD), a leading ...

Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.

Cellular differentiation of stem cells into specialized cells requires many steps, including division, to create more cells; fate determination, which is a commitment to a specific lineage or ...