In a recent study under review at the Scientific Reports journal and currently posted to the Research Square* preprint server, researchers synthesized and evaluated the antitumoral (against several ...
Due to their well-defined three-dimensional geometry, spiro compounds are widely utilized in drug research. From the central tetrahedral carbon atom, besides the regular structure, an inverted spiro ...
Tumor immunotherapies, especially those leveraging T-cells to identify and eliminate cancer cells, represent a major breakthrough in cancer treatment. However, many tumor-associated antigens are not ...
Spiro motifs are compounds that have at least two molecular rings with only one common atom. They are ubiquitous in natural products and bioactive molecules, but despite their wide application in ...
Tumor immunotherapies, especially those leveraging T-cells to identify and eliminate cancer cells, represent a major breakthrough in cancer treatment. However, many tumor-associated antigens are not ...
The early days of drug discovery and development were lonely: scientists in the 19 th century made discoveries often driven by serendipity. Although fortuitous findings continue to happen, we ...
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