There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues at the frontier of biological research. Professor Xi Peng's group at ...
Multi-target single-molecule super-resolution fluorescence microscopy offers a powerful means of understanding the distributions and interplay between multiple subcellular structures at the nanoscale.
A breakthrough in imaging technology promises to transform our understanding of the inner workings of living cells, and provide insights into a wide range of diseases. "It's like taking an airplane ...
Super-resolution (SR) fluorescence microscopy is a powerful tool for visualizing subcellular structures and their dynamic behaviors 1,2,3,4. However, the substantially higher photon budget required ...
To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...
Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of ...
When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...
Both images show individual red blood cells. The one on the right, produced by STED, more clearly shows the Piezo1 proteins (in green), which are a mechanical calcium channel and play a crucial role ...
Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...
Recent years have witnessed great advances in applying deep learning to improve fluorescence microscopy imaging. However, enhancing the fidelity of image restoration networks and improving their ...
A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...
News Medical talks to Samuel Penwell and Winfried Wiegraebe about how the Vutara VXL enables robust, high-throughput 3D super-resolution via single-molecule localization, pairing bi-plane detection ...
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