Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body? There are instances where killer T cells—which are meant to precisely remove virus-infected ...
This milestone expands patient eligibility through multi-HLA targetingBuilds on completed TVGN 489 trial demonstrating 100% viral clearance, no ...
To make the therapy safer and more adaptable, UChicago researchers developed a new “split” system called GA1CAR. This uses ...
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Engineered biomaterial promotes formation of cancer-fighting immune cell clusters
Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary ...
CAMBRIDGE, MA / ACCESS Newswire / November 3, 2025 / Moderna, Inc. (NASDAQ:MRNA) today announced that the first patient has been dosed in a Phase 1/2 study of mRNA-2808, the Company’s investigational ...
T cell therapies have revolutionized cancer treatment—but so far, their success has been largely limited to blood cancers. Solid tumors, which account for around 90% of all adult cancers, remain a ...
A protein notorious for its role in Alzheimer’s disease may hold the key to supercharging the aging immune system, according to new research. Scientists have found that a byproduct of amyloid-beta ...
Once thought to be a flaw in the system, new research suggests that CD4 T cells may actually hold the key to maintaining a properly functioning, age-appropriate immune system. Prof. Alon Monsonego of ...
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KAIST Uncovers the Mechanism Behind Overactive Immune Cells
There are instances where killer T cells—which are meant to precisely remove virus-infected cells—malfunction like overheated ...
Chimeric antigen receptor T-cell therapy has exhibited “compelling” efficacy and safety in lupus, allowing 84% of patients to ...
Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...
Combination with bispecific T-cell engagers amplifies T-cell recruitment and cytotoxic activity against tumor cells -- ...
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