The thrombin time assay is a versatile clinical assay used for screening fibrinogen related disorders and quantification of fibrin degradation products, as well as for detecting the presence of ...

Proteolytic degradation products of fibrinogen, produced as a result of excessive fibrinolysis, have been demonstrated in the blood of cirrhotic patients. 7,8 Such degradation products, when formed in ...

Protein C inhibitor (PCI) is a serpin with many roles in biology, including a dual role as pro- and anticoagulant in blood. The protease specificity and local function of PCI depend on its interaction ...

An interdisciplinary team of researchers from North Carolina State University and the University of North Carolina at Chapel Hill has developed a smart patch designed to monitor a patient's blood and ...

BEDFORD, Mass., Sept. 15, 2014 /PRNewswire/ --Instrumentation Laboratory (IL) today announced the commercialization in Europe of their HemosIL Direct Thrombin Inhibitor (DTI) Assay. When used in ...

Thirteen patients with liver disease and an abnormal prothrombin time refractory to vitamin K therapy were studied (Tables 1 and 2). None of the patients were actively bleeding, and none had received ...

Future Cardiol. 2007;3(4):345-364. Bivalirudin is a derivate of native hirudin. The active substance is a synthetic, 20 amino-acid peptide. The chemical name is ...

A way to effectively stop internal bleeding by magnetically-driven nanoparticles containing thrombin has been found by recent research. A drug based on these nanoparticles can be injected ...