CtIP is a DNA end resection factor widely implicated in alternative end-joining (A-EJ)–mediated translocations in cell-based reporter systems. To address the physiological role of CtIP, an essential ...

Researchers have shown that harmful mutations present in the DNA play an important - yet neglected - role in the conservation and translocation programs of threatened species. Researchers in Lund, ...

Antagonists of growth hormone-releasing hormone potentiate radiation response in prostate cancer. Background: A small subset of human lung cancer harbors the fusion of the gene for echinoderm ...

Inherited retinal degeneration (IRD) encompasses various disorders characterized by progressive loss of retinal photoreceptor cells, ultimately leading to vision loss and blindness. Among the numerous ...

A multi-institution team of researchers led by scientists at Baylor College of Medicine has discovered a genetic signature that can identify drivers of poor outcomes in advanced estrogen-receptor ...

Translocation is a genetic abnormality in which part of a chromosome moves to another chromosome. Chromosomes are genetic structures within cells that hold genes. When translocation occurs, it causes ...

A combination of genetic mutations may explain the higher incidence of and poorer outcomes from pediatric leukemia in Hispanic and Latino children, according to Penn State College of Medicine ...

The new classifications included several major changes and may help identify different subtypes. The fifth edition of the World Health Organization classification (2022 WHO) and the International ...

Researchers at the Scripps Research Institute in Florida have made a clinical discovery that could help physicians develop new treatments for an oral cancer that affects the salivary glands, according ...