Figure 1: a Sequence alignment of the central domains of human XPA and other XPAs. The solution structure of the central domain of XPA was solved by multidimensional double and triple resonance NMR ...
ATR (ATM and Rad3-related) is an essential regulator of the nucleotide excision repair (NER) mechanism. For NER activation, ATR phosphorylates XPA, the rate-limiting factor in the NER pathway. However ...
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