Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought. The ...

Scientists have discovered that a gene called MUC19, inherited from Denisovans through ancient interbreeding, may have played a vital role in helping Indigenous ancestors adapt as they migrated into ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Researchers have significantly expanded the catalogue of known human genetic variation. The resulting datasets, shared in two back-to-back publications in the journal Nature, constitute what may be ...

Believe it or not, evolution isn’t blind or random chance. It is the natural result of having an advantage, even if it is very slight, that makes the difference between dying young or living to ...

Researchers have identified how variations in a gene called TRIO can influence brain functions and result in distinct neurodevelopmental diseases. The study, published in the journal eLife, could pave ...

The fossil and genetic evidence agree that modern humans originated in Africa. The most genetically diverse human populations—the groups that have had the longest time to pick up novel mutations—live ...

A new study in the Proceedings of the National Academy of Sciences finds that differences between Neanderthal and early ...