DNA has to be carefully organized and packaged so it will fit into the nucleus of cells; compacted DNA that's been organized with other proteins is known as chromatin. The structure of the genome can ...

A bacterial protein helps to stop transcription -- the process of making RNA copies of DNA to carry out the functions of the cell -- by causing the cellular machinery that transcribes the DNA to ...

A team of researchers has found that transcription factors have a tendency to bind strongly to 'mismatched' sections of DNA, i.e. sections of the genome that were not copied correctly. The strong ...

Transcription and replication occur at high frequency in cells. As they share the same DNA template, a high incidence of encounters is expected between the transcription and replication ...

How chromatin responds to transcription-blocking DNA lesions is unclear. This study reveals that RNA polymerase II (RNAPII) ...

(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human ...

Transcription is the process by which DNA is converted into messenger RNA in preparation for translation into a functional product. Extrinsic agents, such as ionizing radiation or chemical mutagen ...

In addition to BRCA1’s role in repairing DNA damage and preventing it from accumulating across the genome, the study indicates this invaluable protein appears to improve transcription fidelity.

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism ...

Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H2S) signaling, report researchers from Japan. Heme binding promotes the reaction of H2S with the transcription ...