Researchers from Wuhan Institute of Biomedical Sciences, Jianghan University and collaborators recently showed that activating the endogenous transcription factors Ngn2 and Isl1 via CRISPRa can ...

Delivering a connection-building protein to star-shaped cells in the brain could reverse changes to neural circuits seen in ...

CAMBRIDGE, MA -- The human brain contains about 86 billion neurons. These cells fire electrical signals that help the brain store memories and send information and commands throughout the brain and ...

Neurons and glial cells are like dance partners in the brain, coordinating moves that shape how signals flow and how excitable neurons become. Astrocytes, star-shaped glial cells, can reshape ...

When it comes to brain function, neurons get a lot of the glory. But healthy brains depend on the cooperation of many kinds of cells. The most abundant of the brain's non-neuronal cells are astrocytes ...

Cells feature an array of biological cascades to respond to stressors such as protein aggregates, viruses, and DNA damage. When these pathways are activated too much or for too long, things can go ...