Murphy et al. reveal a unifying pathogenetic mechanism according to which diverse mutations in the muscle-specific ribosomal protein RPL3L cause severe neonatal dilated cardiomyopathy, establishing a ...

Emphysema is a chronic lung condition characterised by the destruction of alveolar walls. This pathophysiology involves damage that impairs the lungs' ability to recoil: decreasing airflow and causing ...

The area addressed is vast—a single Medline search with the term “molecular mechanisms atrial fibrillation” revealed 611 papers. We have therefore chosen to focus on clinically relevant mechanisms ...

Background The National Institute for Health and Care Excellence (NICE) guidelines do not currently recommend the use of salbutamol in infants under the age of 2 years due to lack of evidence of ...

Ulcerative colitis is a chronic condition that causes inflammation in the colon. Some environmental triggers, like smoking and certain drugs, may lead to the development of IBD. Ulcerative colitis is ...