Powerball numbers and jackpot results for $264 million lottery drawing Wednesday, July 16, 2025. Who won? Winning numbers, next drawing, tickets and more.

The winning numbers from the Wednesday, July 16 drawing are 4, 21, 43, 48 and 49. The Powerball was 22 . The Power Play multiplier was 2x. Check back to see if anyone won the Powerball jackpot.

An Oakland County woman on a camping trip in Northern Michigan won the Michigan Lottery's Fantasy 5 jackpot from the July 3 drawing.