New England Patriots quarterback Jacoby Brissett finds tight end Hunter Henry to move the chains against the San Francisco ...

San Francisco 49ers defensive lineman Sam Okuayinonu forced a fumble against New England Patriots running back Rhamondre ...

San Francisco 49ers quarterback Brock Purdy found wide receiver Brandon Aiyuk for a 38-yard gain against the New England ...

After winning their opening games of the season, both San Francisco and New England have lost their last two games.

The Patriots enter their Week 4 matchup against San Francisco 1-3, coming off a deflating 24-3 loss to the Jets. The 49ers ...

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The Patriots look to reach .500 for the first time in years as they take on the 49ers in California. Follow along for live ...

The 49ers face a must-win game in week 4 at home against an inconsistent young New England team.  The Patriots believe they are the team that beat Cincinnati on ...

Jordan Mason has taken the bull by the horns in the 49ers backfield sans Christian McCaffrey, and our NFL betting picks ...

The San Francisco 49ers face the New England Patriots at 1:05 p.m. PDT on Sunday, Sept. 29 at Levi’s Stadium in Santa Clara, ...

The Patriots have a big Week 4 matchup against the 49ers, so let's check out three bold predictions for them in this game.