Activating two somatostatin receptors enhances amyloid beta breakdown and improves memory in models of Alzheimer’s disease.

Grafton Therapeutics Sarl has identified halogenated somatostatin analogues acting as somatostatin SST2 receptor and/or SST5 receptor agonists reported to be useful for the treatment of cancer.

Researchers at Karolinska Institutet in Sweden and the RIKEN Center for Brain Science in Japan have identified two receptors in the brain that control the breakdown of amyloid beta, a substance that ...

Agents that directly lower ACTH secretion by a pituitary adenoma represent an attractive option for the treatment of Cushing's disease, as these drugs directly target the pathogenesis of disease.

Somatostatin receptors (SSTRs) constitute a crucial family of G protein-coupled receptors (GPCRs) that play pivotal roles in regulating hormone secretion and inhibiting tumor growth. Among five ...

Takeda Pharmaceutical Co. Ltd. has identified N-(pyrrolidin-3-yl or piperidin-4-yl)acetamide derivatives acting as somatostatin SST4 receptor agonists and thus reported to be useful for the treatment ...