The mitotic spindle is positioned with respect to asymmetries in cellular polarity to ensure that the partitioning of genomes is coordinated with the partitioning of developmental determinants. A ...
Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...
When a cell divides, it performs a feat of microscopic choreography—duplicating its DNA and depositing it into two new cells. The spindle is the machinery behind that process: It latches onto ...
Spindles are responsible for pulling apart your chromosomes when your cells divide. New research confirms a theory that these spindles self-organize and interact with one another much like active ...
Researchers at Waseda University in Japan have for the first time directly observed the "molecular motor", called Xkid, that plays a critical role in facilitating the proper alignment of chromosomes ...
Microtubule motor proteins can be either plus end motors or minus end motors depending on the direction of movement. Mitosis requires the trafficking of proteins along microtubules to produce two ...