Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Spinal cord injury (SCI) remains one of the most devastating medical conditions, severely impacting quality of life and often leading to permanent disability. The central nervous system (CNS) has a ...

Young minds are easily molded. Each new experience rewires a child’s brain circuitry, adding and removing synaptic connections between neurons. These wiring patterns become more stable with age, but ...

In a recent review published in Experimental & Molecular Medicine, researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2). Study: Lipocalin-2: a ...

Why do some people remain healthy through childhood yet become more vulnerable to brain disorders such as dementia later in life? A KAIST (President Kwang Hyung Lee) -led team has uncovered a key part ...

The mechanism of astrocytic autophagy plasticity plays a crucial role in AD. When the autophagy-regulating genes (LC3B and SQSTM1) in astrocytes are activated, Aβ is efficiently removed, which is ...

Delivering a connection-building protein to star-shaped cells in the brain could reverse changes to neural circuits seen in Down syndrome, according to new research my colleagues and I published in ...

Please provide your email address to receive an email when new articles are posted on . A Boston-area clinical stage drug discovery and development company announced $6 million in pre-Series B bridge ...

Why do some people remain healthy through childhood yet become more vulnerable to brain disorders such as dementia later in life? A KAIST-led team has uncovered a key part of the answer: a ...