President Trump is reportedly dispatching his newly confirmed Secretary of State Marco Rubio to Panama for his first foreign trip. Here's what's at stake.

Trump's new top maritime official Louis Sola tells CNBC 'all options on the table' to punish Panama and defend U.S. business, trade and national security.

US senators heard sharply different analyses about Chinese influence over the Panama Canal on Wednesday, with some experts suggesting solutions ranging from enhanced trade partnerships to military intervention to regain control of the strategic waterway.

The Tuesday hearing delved into security issues and foreign influence on the foremost maritime channel connecting the Atlantic and Pacific Oceans.

Trump could make history by leading the charge for Puerto Rican statehood. He would achieve many of the same goals behind his push for Canada, Greenland and the Panama Canal.

Amid Trump’s bid to acquire Greenland, Rep. Andy Ogles (R-TN) also stressed the need to properly compete with China and “send them back to their own hemisphere.” He added that Trump publicly expressing interest in Greenland is “broadcasting” that “America is great again.”

This is not about acquiring land for the purpose of acquiring land,” Rubio. “This is in our national interest and it needs to be solved.”

It’s impossible, I can’t negotiate,” Mulino said when asked about returning the canal to U.S. control. “That is done. The canal belongs to Panama.”

Panama President José Raúl Mulino said Thursday there will be no negotiation with the United States over ownership of the Panama Canal.

Panama President José Raúl Mulino has a message for Secretary of State Marco Rubio ahead of his impending diplomatic visit: The Panama Canal is not up for discussion. “It’s impossible,” Munilo said in Spanish at a press conference in Panama City on Thursday.