49ers san francisco news

San Francisco 49ers vs. Indianapolis Colts for NFL Week 16

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· 14h · on MSN

NFL injury report, update: San Francisco 49ers vs Indianapolis Colts for NFL Week 16

The Indianapolis Colts host the San Francisco 49ers on " Monday Night Football " in NFL Week 16 action.

· 19h · on MSN

Stock up, down after Tennessee Titans' Week 15 loss to San Francisco 49ers

· 2d

49ers Week 15 rooting guide: Who San Francisco should pull for?

NFL · 1d

Colts vs. Seahawks highlights | Week 15

Highlights from the Week 15 matchup between the Indianapolis Colts and the Seattle Seahawks during the 2025 NFL season.

· 1d

Top Seahawks takeaways from 18-16 victory over Indianapolis Colts

· 1d

Seahawks avoid disaster and narrowly defeat Colts 18-16 in Week 15

49ers, Titans

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San Francisco 49ers · 15h

Morning Report: Recap of 49ers Post-Bye Week Win Over Titans ️

The San Francisco 49ers hosted a special halftime ceremony on Sunday to celebrate the induction of three-time Super Bowl champion Brent Jones into the Edward J. DeBartolo Sr. San Francisco 49ers Hall of Fame. Jerry Rice introduced Jones, who became the 33rd member to receive the honor.

USA TODAY Touchdown Wire on MSN · 1d

Worst performances from 49ers' unsatisfying win vs. Titans in Week 15

Las Vegas Sun · 1d

Purdy's 3 TD passes lead 49ers to 37-24 win over Titans

· 15h

Who was the Tennessee Titans highest graded player in Week 15 loss?

The Tennessee Titans fell to the San Francisco 49ers 37-24 in Week 15, and while the score showcases the 49ers' dominance, it says nothing about the effort put in by the Titans.

· 1d

Instant analysis of 49ers’ 37-24 victory over the Titans for 10th win of season

· 7h

49ers Hit With Bad News About Big Potential Offseason Departure

· 1d

49ers grades for Brock Purdy's three-touchdown effort in Week 15 win over Titans

Purdy took advantage of the Titans’ defensive deficiencies to string together five consecutive scoring drives to open the game.

· 1d

3 quick takeaways from the 49ers blowout win over the Titans: Brock keeps the offense rolling

· 1d

Titans vs 49ers Predictions, Picks & Best Bets for Today's NFL Week 15 Game

49ers, Brandon Aiyuk and Kyle Shanahan

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· 18h · on MSN

49ers’ Kyle Shanahan Makes Shocking Admission on Fallout With Brandon Aiyuk

The San Francisco 49ers have been on a tear despite their multitude of injuries in 2025.

· 19h

Kyle Shanahan bluntly explains 49ers decision on WR Brandon Aiyuk

· 1d

Coach Kyle Shanahan explains why the 49ers placed Brandon Aiyuk on season-ending reserve list

· 14h

Kyle Shanahan hasn’t seen Brandon Aiyuk ‘in a month’ as 49ers breakup looms

Brandon Aiyuk and the 49ers have kept their relationship long-distance as a divorce inevitably looms.

· 15h

Kyle Shanahan on Brandon Aiyuk returning: ‘Not one point was I really planning on it’

· 1d

49ers officially end Brandon Aiyuk’s season as his future with team remains murky

19h

How are the hobbled 49ers still in this? They found a different way to be great

Two defensive stars were lost for the season. Their QB missed multiple games. Still, here are the 49ers are, a game out of the No. 1 seed.

49ers Webzone

49ers Playoff Picture: San Francisco Postseason Deep Dive and Rooting Guide

How Week 14 games impact San Francisco's NFC seeding, postseason path, and key rooting interests in a tight playoff race.

49ers vs. Titans prediction: San Francisco will make the most of golden opportunity to keep pace in NFC West

Need to know. Brock off a bye. 49ers quarterback Brock Purdy has played two games off a bye in his career, and he has been nearly perfect in both. In those two g

22h

49ers’ Ricky Pearsall performs like the heir to Brandon Aiyuk in win over Titans

It's clear the 49ers are relying on Pearsall to become Aiyuk's successor in the receiving corps — this season and in the future.

1don MSN

Studs and duds from Tennessee Titans' 37-24 loss to San Francisco 49ers

Here's a look at the studs and duds (and those in between) from the Tennessee Titans' 37-24 loss to the San Francisco 49ers in Week 15.

12hon MSN

Defensive tackle Jeffery Simmons has home broken into during Titans’ road trip to San Francisco

The Tennessee Titans say the home of defensive tackle Jeffery Simmons was burglarized while he was on the road in San Francisco.

1don MSN

49ers vs. Titans: Where to watch NFL Week 15, betting odds, score prediction, sportsbook promos, SGP picks

The 49ers are 12.5-point favorites, per the latest Titans vs. 49ers odds, and the over/under for total points scored is 44.5 at DraftKings. The 49ers are -901 money line favorites (risk $901 to win $100),

USA TODAY Touchdown Wire on MSN

49ers injury update: Christian McCaffrey active vs. Titans

Christian McCaffrey is officially active for the San Francisco 49ers on Sunday when they host the Tennessee Titans at Levi's Stadium. McCaffrey was a late addition to the injury report when the 49ers on Saturday downgraded him to questionable with a back injury.